Mutations that silence constitutive signaling activity in the allosteric ligand-binding site of the thyrotropin receptor

Eitemau Tebyg

• Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor
  gan: Kleinau, Gunnar, et al.
  Cyhoeddwyd: (2010)
• From Molecular Details of the Interplay between Transmembrane Helices of the Thyrotropin Receptor to General Aspects of Signal Transduction in Family A G-protein-coupled Receptors (GPCRs)
  gan: Kleinau, Gunnar, et al.
  Cyhoeddwyd: (2011)
• Molecular sampling of the allosteric binding pocket of the TSH receptor provides discriminative pharmacophores for antagonist and agonists
  gan: Hoyer, Inna, et al.
  Cyhoeddwyd: (2013)
• Constitutively Active Thyrotropin And Thyrotropin-Releasing Hormone Receptors And Their Inverse Agonists
  gan: Neumann, Susanne, et al.
  Cyhoeddwyd: (2010)
• Defining Structural and Functional Dimensions of the Extracellular Thyrotropin Receptor Region
  gan: Kleinau, Gunnar, et al.
  Cyhoeddwyd: (2011)