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Photochemically and chemically activatable antisense oligonucleotides: comparison of their reactivities towards DNA and RNA targets.

Dodecadeoxyribonucleotides derivatized with 1,10-phenanthroline or psoralen were targeted to the point mutation (G<-->U) in codon 12 of the Ha-ras mRNA. DNA and RNA fragments, 27 nucleotides in length, and containing the complementary sequence of the 12mers, were used to compare the reactivity...

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Bibliografski detalji
Glavni autori: Godard, G, François, J C, Duroux, I, Asseline, U, Chassignol, M, Nguyen, T, Hélène, C, Saison-Behmoaras, T
Format: Artigo
Jezik:Inglês
Izdano: 1994
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC308531/
https://ncbi.nlm.nih.gov/pubmed/7527139
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