Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate.

Homopyrimidine oligodeoxynucleotides recognize the major groove of the DNA double helix at homopurine.homopyrimidine sequences by forming local triple helices. Phenanthroline was covalently attached to the 5' end of an 11-mer homopyrimidine oligonucleotide of sequence d(TTTCCTCCTCT). Simian virus 40...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	François, J C, Saison-Behmoaras, T, Barbier, C, Chassignol, M, Thuong, N T, Hélène, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2557624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.9702
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