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Direct Oligonucleotide-Photosensitizer Conjugates for Photochemical Delivery of Antisense Oligonucleotides()

Activation of photosensitizers in endosomes enables release of therapeutic macromolecules into cytosol of the target cells for pharmacological actions. In this study, we demonstrate that direct conjugation of photosensitizer to oligonucleotides (ONs) allows spatial and temporal co-localization of th...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Yuan, Ahu, Laing, Brian, Hu, Yiqiao, Ming, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405145/
https://ncbi.nlm.nih.gov/pubmed/25786195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc00573f
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