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Direct Oligonucleotide-Photosensitizer Conjugates for Photochemical Delivery of Antisense Oligonucleotides()

Activation of photosensitizers in endosomes enables release of therapeutic macromolecules into cytosol of the target cells for pharmacological actions. In this study, we demonstrate that direct conjugation of photosensitizer to oligonucleotides (ONs) allows spatial and temporal co-localization of th...

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Bibliografische gegevens
Gepubliceerd in:Chem Commun (Camb)
Hoofdauteurs: Yuan, Ahu, Laing, Brian, Hu, Yiqiao, Ming, Xin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405145/
https://ncbi.nlm.nih.gov/pubmed/25786195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc00573f
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