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Bioconjugates for Targeted Delivery of Therapeutic Oligonucleotides

Bioconjugates have been used to deliver therapeutic oligonucleotides to their pharmacological targets in diseased cells. Molecular-scale conjugates can be prepared by directly linking targeting ligands with oligonucleotides and the resultant conjugates can selectively bind to cell surface receptors...

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Publicado en:Adv Drug Deliv Rev
Autores principales: Ming, Xin, Laing, Brian
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504788/
https://ncbi.nlm.nih.gov/pubmed/25689735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2015.02.002
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