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Direct Oligonucleotide-Photosensitizer Conjugates for Photochemical Delivery of Antisense Oligonucleotides()

Activation of photosensitizers in endosomes enables release of therapeutic macromolecules into cytosol of the target cells for pharmacological actions. In this study, we demonstrate that direct conjugation of photosensitizer to oligonucleotides (ONs) allows spatial and temporal co-localization of th...

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Detaylı Bibliyografya
Yayımlandı:Chem Commun (Camb)
Asıl Yazarlar: Yuan, Ahu, Laing, Brian, Hu, Yiqiao, Ming, Xin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405145/
https://ncbi.nlm.nih.gov/pubmed/25786195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc00573f
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