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Photochemically and chemically activatable antisense oligonucleotides: comparison of their reactivities towards DNA and RNA targets.
Dodecadeoxyribonucleotides derivatized with 1,10-phenanthroline or psoralen were targeted to the point mutation (G<-->U) in codon 12 of the Ha-ras mRNA. DNA and RNA fragments, 27 nucleotides in length, and containing the complementary sequence of the 12mers, were used to compare the reactivity...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1994
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC308531/ https://ncbi.nlm.nih.gov/pubmed/7527139 |
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