Alterations in Nucleolar Structure and Gene Expression Programs in Prostatic Neoplasia Are Driven by the MYC Oncogene

Increased nucleolar size and number are hallmark features of many cancers. In prostate cancer, nucleolar enlargement and increased numbers are some of the earliest morphological changes associated with development of premalignant prostate intraepithelial neoplasia (PIN) lesions and invasive adenocar...

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Detalhes bibliográficos
Main Authors: Koh, Cheryl M., Gurel, Bora, Sutcliffe, Siobhan, Aryee, Martin J., Schultz, Denise, Iwata, Tsuyoshi, Uemura, Motohide, Zeller, Karen I., Anele, Uzoma, Zheng, Qizhi, Hicks, Jessica L., Nelson, William G., Dang, Chi V., Yegnasubramanian, Srinivasan, De Marzo, Angelo M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078425/
https://ncbi.nlm.nih.gov/pubmed/21435462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.040
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