Nuclear MYC Protein Overexpression is an Early Alteration in Human Prostate Carcinogenesis

The MYC onco-protein is a transcription factor that regulates cell proliferation, metabolism, protein synthesis, mitochondrial function and stem cell renewal. A region on chromosome 8q24 encompassing the MYC locus is amplified in prostate cancer, but this occurs mostly in advanced disease suggesting...

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Hauptverfasser: Gurel, Bora, Iwata, Tsuyoshi, Koh, Cheryl, Jenkins, Robert B., Lan, Fusheng, Van Dang, Chi, Hicks, Jessica L., Morgan, James, Cornish, Toby C., Sutcliffe, Siobhan, Isaacs, William B., Luo, Jun, De Marzo, Angelo M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170853/
https://ncbi.nlm.nih.gov/pubmed/18567993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2008.111
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