Alterations in Nucleolar Structure and Gene Expression Programs in Prostatic Neoplasia Are Driven by the MYC Oncogene

Increased nucleolar size and number are hallmark features of many cancers. In prostate cancer, nucleolar enlargement and increased numbers are some of the earliest morphological changes associated with development of premalignant prostate intraepithelial neoplasia (PIN) lesions and invasive adenocar...

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Main Authors: Koh, Cheryl M., Gurel, Bora, Sutcliffe, Siobhan, Aryee, Martin J., Schultz, Denise, Iwata, Tsuyoshi, Uemura, Motohide, Zeller, Karen I., Anele, Uzoma, Zheng, Qizhi, Hicks, Jessica L., Nelson, William G., Dang, Chi V., Yegnasubramanian, Srinivasan, De Marzo, Angelo M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078425/
https://ncbi.nlm.nih.gov/pubmed/21435462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.040
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