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Donation of catalytic residues to RNA polymerase active center by transcription factor Gre

During transcription elongation, RNA polymerase (RNAP) occasionally loses its grip on the growing RNA end and backtracks on the DNA template. Prokaryotic Gre factors rescue the backtracked ternary elongating complex through stimulation of an intrinsic endonuclease activity, which removes the disenga...

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Detalles Bibliográficos
Main Authors: Sosunova, Ekaterina, Sosunov, Vasily, Kozlov, Maxim, Nikiforov, Vadim, Goldfarb, Alex, Mustaev, Arkady
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC307591/
https://ncbi.nlm.nih.gov/pubmed/14668436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536698100
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