Modular organization of the catalytic center of RNA polymerase

The Fe(2+) ion that specifically replaces Mg(2+) in the active center of RNA polymerase generates reactive hydroxyl radicals that cause highly localized cleavage of polypeptide chains. Mapping of the cleavage sites revealed the overall architecture of the active center. Nine distinct sites, five in...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Mustaev, Arkady, Kozlov, Maxim, Markovtsov, Vadim, Zaychikov, Evgeny, Denissova, Ludmila, Goldfarb, Alex
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192618/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6641
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