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Modular organization of the catalytic center of RNA polymerase

The Fe(2+) ion that specifically replaces Mg(2+) in the active center of RNA polymerase generates reactive hydroxyl radicals that cause highly localized cleavage of polypeptide chains. Mapping of the cleavage sites revealed the overall architecture of the active center. Nine distinct sites, five in...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Mustaev, Arkady, Kozlov, Maxim, Markovtsov, Vadim, Zaychikov, Evgeny, Denissova, Ludmila, Goldfarb, Alex
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6641
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