Modular organization of the catalytic center of RNA polymerase
The Fe(2+) ion that specifically replaces Mg(2+) in the active center of RNA polymerase generates reactive hydroxyl radicals that cause highly localized cleavage of polypeptide chains. Mapping of the cleavage sites revealed the overall architecture of the active center. Nine distinct sites, five in...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192618/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6641 |
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