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Modular organization of the catalytic center of RNA polymerase

The Fe(2+) ion that specifically replaces Mg(2+) in the active center of RNA polymerase generates reactive hydroxyl radicals that cause highly localized cleavage of polypeptide chains. Mapping of the cleavage sites revealed the overall architecture of the active center. Nine distinct sites, five in...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Mustaev, Arkady, Kozlov, Maxim, Markovtsov, Vadim, Zaychikov, Evgeny, Denissova, Ludmila, Goldfarb, Alex
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6641
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