Modular organization of the catalytic center of RNA polymerase

The Fe(2+) ion that specifically replaces Mg(2+) in the active center of RNA polymerase generates reactive hydroxyl radicals that cause highly localized cleavage of polypeptide chains. Mapping of the cleavage sites revealed the overall architecture of the active center. Nine distinct sites, five in...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Mustaev, Arkady, Kozlov, Maxim, Markovtsov, Vadim, Zaychikov, Evgeny, Denissova, Ludmila, Goldfarb, Alex
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192618/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6641
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