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Donation of catalytic residues to RNA polymerase active center by transcription factor Gre

During transcription elongation, RNA polymerase (RNAP) occasionally loses its grip on the growing RNA end and backtracks on the DNA template. Prokaryotic Gre factors rescue the backtracked ternary elongating complex through stimulation of an intrinsic endonuclease activity, which removes the disenga...

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Hlavní autoři: Sosunova, Ekaterina, Sosunov, Vasily, Kozlov, Maxim, Nikiforov, Vadim, Goldfarb, Alex, Mustaev, Arkady
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC307591/
https://ncbi.nlm.nih.gov/pubmed/14668436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536698100
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