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The involvement of the aspartate triad of the active center in all catalytic activities of multisubunit RNA polymerase

Three conserved aspartate residues in the largest subunit of multisubunit RNA polymerases (RNAPs) coordinate two Mg(2+) ions involved in the catalysis of phosphodiester bond synthesis. A structural model based on the stereochemistry of nucleotidyl transfer reaction as well as recent crystallographic...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Sosunov, Vasily, Zorov, Savva, Sosunova, Ekaterina, Nikolaev, Anatoly, Zakeyeva, Irina, Bass, Irina, Goldfarb, Alex, Nikiforov, Vadim, Severinov, Konstantin, Mustaev, Arkady
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180743/
https://ncbi.nlm.nih.gov/pubmed/16049026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki688
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