The involvement of the aspartate triad of the active center in all catalytic activities of multisubunit RNA polymerase

Three conserved aspartate residues in the largest subunit of multisubunit RNA polymerases (RNAPs) coordinate two Mg(2+) ions involved in the catalysis of phosphodiester bond synthesis. A structural model based on the stereochemistry of nucleotidyl transfer reaction as well as recent crystallographic...

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Main Authors: Sosunov, Vasily, Zorov, Savva, Sosunova, Ekaterina, Nikolaev, Anatoly, Zakeyeva, Irina, Bass, Irina, Goldfarb, Alex, Nikiforov, Vadim, Severinov, Konstantin, Mustaev, Arkady
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180743/
https://ncbi.nlm.nih.gov/pubmed/16049026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki688
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