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Donation of catalytic residues to RNA polymerase active center by transcription factor Gre

During transcription elongation, RNA polymerase (RNAP) occasionally loses its grip on the growing RNA end and backtracks on the DNA template. Prokaryotic Gre factors rescue the backtracked ternary elongating complex through stimulation of an intrinsic endonuclease activity, which removes the disenga...

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Bibliografske podrobnosti
Main Authors: Sosunova, Ekaterina, Sosunov, Vasily, Kozlov, Maxim, Nikiforov, Vadim, Goldfarb, Alex, Mustaev, Arkady
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC307591/
https://ncbi.nlm.nih.gov/pubmed/14668436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536698100
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