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Donation of catalytic residues to RNA polymerase active center by transcription factor Gre
During transcription elongation, RNA polymerase (RNAP) occasionally loses its grip on the growing RNA end and backtracks on the DNA template. Prokaryotic Gre factors rescue the backtracked ternary elongating complex through stimulation of an intrinsic endonuclease activity, which removes the disenga...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307591/ https://ncbi.nlm.nih.gov/pubmed/14668436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536698100 |
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