A mutant HpaII methyltransferase functions as a mutator enzyme.
DNA (cytosine-5)-methyltransferases can cause deamination of cytosine when the cofactor S-adenosylmethionine (AdoMet) is limiting and thus function as sequence-specific C-->U mutator enzymes. Here we explored whether mutations causing inactivation of the cofactor binding activity of the HpaII methyl...
-д хадгалсан:
| -д хэвлэсэн: | Nucleic Acids Res |
|---|---|
| Үндсэн зохиолчид: | , , , , |
| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Oxford University Press
1995
|
| Онлайн хандалт: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4275 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
|