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High level expression and purification of HhaI methyltransferase.

A cloning system for the DNA-(cytosine-5)-methyltransferase MHhaI and high level expression of the enzyme are described. A parent plasmid was constructed from fragments of the MHhaI gene and synthetic oligonucleotides. The construct permits introduction of various restriction sites for cloning at pr...

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Publicat a:Nucleic Acids Res
Autors principals: Wu, J C, Santi, D V
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1988
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334686/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3340551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.2.703
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