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Synthesis and Biological Evaluation of New 2-Alkylaminoethyl-1,1-Bisphosphonic Acids against Trypanosoma cruzi and Toxoplasma gondii targeting Farnesyl Diphosphate Synthase
The effect of long chain 2-alkylaminoethyl-1,1-bisphosphonates against proliferation of the clinically more relevant form of Trypanosoma cruzi, the etiologic agent of American trypanosomiasis (Chagas’ disease), and against tachyzoites of Toxoplasma gondii was investigated. Particularly, compound 26...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071284/ https://ncbi.nlm.nih.gov/pubmed/21419634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.02.037 |
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