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Synthesis and Biological Evaluation of 1-Alkylaminomethyl-1,1-Bisphosphonic Acids against Trypanosoma cruzi and Toxoplasma gondii

As an extension of our project aimed at the search for new chemotherapeutic agents against Chagas disease and toxoplasmosis, several 1,1-bisphosphonates were designed, synthesized and biologically evaluated against Trypanosoma cruzi and Toxoplasma gondii, the etiologic agents of these diseases, resp...

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Vydáno v:Bioorg Med Chem
Hlavní autoři: Galaka, Tamila, Falcone, Bruno N., Li, Catherine, Szajnman, Sergio H., Moreno, Silvia N. J., Docampo, Roberto, Rodriguez, Juan B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660996/
https://ncbi.nlm.nih.gov/pubmed/31296439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.07.004
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