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Synthesis and Biological Evaluation of New 2-Alkylaminoethyl-1,1-Bisphosphonic Acids against Trypanosoma cruzi and Toxoplasma gondii targeting Farnesyl Diphosphate Synthase

The effect of long chain 2-alkylaminoethyl-1,1-bisphosphonates against proliferation of the clinically more relevant form of Trypanosoma cruzi, the etiologic agent of American trypanosomiasis (Chagas’ disease), and against tachyzoites of Toxoplasma gondii was investigated. Particularly, compound 26...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Rosso, Valeria S., Szajnman, Sergio H., Malayil, Leena, Galizzi, Melina, Moreno, Silvia N. J., Docampo, Roberto, Rodriguez, Juan B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071284/
https://ncbi.nlm.nih.gov/pubmed/21419634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.02.037
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