Synthesis and Biological Evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting Farnesyl Diphosphate Synthase

The effect of a series of 2-alkylaminoethyl-1,1-bisphosphonic acids against proliferation of the clinically more relevant form of Trypanosoma cruzi, the etiologic agent of American trypanosomiasis (Chagas’ disease), and against tachyzoites of Toxoplasma gondii has been studied. Most of these drugs e...

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Bibliografiset tiedot
Päätekijät: Szajnman, Sergio H., García Liñares, Guadalupe E., Li, Zhu-Hong, Jiang, Cuiying, Galizzi, Melina, Bontempi, Esteban J., Ferella, Marcela, Moreno, Silvia N. J., Docampo, Roberto, Rodriguez, Juan B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330165/
https://ncbi.nlm.nih.gov/pubmed/18096393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.12.010
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