Synthesis and Biological Evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting Farnesyl Diphosphate Synthase

The effect of a series of 2-alkylaminoethyl-1,1-bisphosphonic acids against proliferation of the clinically more relevant form of Trypanosoma cruzi, the etiologic agent of American trypanosomiasis (Chagas’ disease), and against tachyzoites of Toxoplasma gondii has been studied. Most of these drugs e...

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Detaylı Bibliyografya
Asıl Yazarlar: Szajnman, Sergio H., García Liñares, Guadalupe E., Li, Zhu-Hong, Jiang, Cuiying, Galizzi, Melina, Bontempi, Esteban J., Ferella, Marcela, Moreno, Silvia N. J., Docampo, Roberto, Rodriguez, Juan B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330165/
https://ncbi.nlm.nih.gov/pubmed/18096393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.12.010
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