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Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes
Previous authors have suggested that tumor suppressor expression promotes aging while preventing cancer, but direct experimental support for this cancer-aging hypothesis has been elusive. Here, by using somatic, tissue-specific inactivation of the p16(INK4a) tumor suppressor in murine T- or B-lympho...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069667/ https://ncbi.nlm.nih.gov/pubmed/21245485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-304402 |
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