Comparative Analysis of the Biosynthetic Gene Clusters and Pathways for Three Structurally Related Antitumor Antibiotics Bleomycin, Tallysomycin and Zorbamycin

The biosynthetic gene clusters for the glycopeptide antitumor antibiotics bleomycin (BLM), tallysomycin (TLM), and zorbamycin (ZBM) have been recently cloned and characterized from Streptomyces verticillus ATCC15003, Streptoalloteichus hindustanus E465-94 ATCC31158, and Streptomyces flavoviridis ATC...

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Detalhes bibliográficos
Main Authors: Galm, Ute, Wendt-Pienkowski, Evelyn, Wang, Liyan, Huang, Sheng-Xiong, Unsin, Claudia, Tao, Meifeng, Coughlin, Jane M., Shen, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064724/
https://ncbi.nlm.nih.gov/pubmed/21210656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np1008152
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