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Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition

Trim5α is a host antiviral protein that recognizes incoming retroviral capsids in the cytoplasm and prevents productive infections. Although present in most mammals, the state of the Trim5 gene is dynamic in that primates have one copy with several splice variants, while rodents and cows have multip...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Tareen, Semih U., Emerman, Michael
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051842/
https://ncbi.nlm.nih.gov/pubmed/21035162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.09.018
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