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Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5α restriction factor
The host restriction factor TRIM5α mediates species-specific, early blocks to retrovirus infection; susceptibility to these blocks is determined by viral capsid sequences. Here we demonstrate that TRIM5α variants from Old World monkeys specifically associate with the HIV type 1 (HIV-1) capsid and th...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459386/ https://ncbi.nlm.nih.gov/pubmed/16540544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509996103 |
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