The Human TRIM5α Restriction Factor Mediates Accelerated Uncoating of the N-Tropic Murine Leukemia Virus Capsid

The host cell factors TRIM5α(hu) and Fv-1 restrict N-tropic murine leukemia virus (N-MLV) infection at an early postentry step before or after reverse transcription, respectively. Interestingly, the identity of residue 110 of the MLV capsid determines susceptibility to both TRIM5α(hu) and Fv-1. In t...

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Detalhes bibliográficos
Main Authors: Perron, Michel J., Stremlau, Matthew, Lee, Mark, Javanbakht, Hassan, Song, Byeongwoon, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865943/
https://ncbi.nlm.nih.gov/pubmed/17135314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02318-06
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