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Modulation of Retroviral Restriction and Proteasome Inhibitor-Resistant Turnover by Changes in the TRIM5α B-Box 2 Domain

An intact B-box 2 domain is essential for the antiretroviral activity of TRIM5α. We modeled the structure of the B-box 2 domain of TRIM5α based on the existing three-dimensional structure of the B-box 2 domain of human TRIM29. Using this model, we altered the residues predicted to be exposed on the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Diaz-Griffero, Felipe, Kar, Alak, Perron, Michel, Xiang, Shi-Hua, Javanbakht, Hassan, Li, Xing, Sodroski, Joseph
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045480/
https://ncbi.nlm.nih.gov/pubmed/17626085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00703-07
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