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Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition

Trim5α is a host antiviral protein that recognizes incoming retroviral capsids in the cytoplasm and prevents productive infections. Although present in most mammals, the state of the Trim5 gene is dynamic in that primates have one copy with several splice variants, while rodents and cows have multip...

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Detalhes bibliográficos
Main Authors: Tareen, Semih U., Emerman, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051842/
https://ncbi.nlm.nih.gov/pubmed/21035162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.09.018
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