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Impaired insulin secretion in transgenic mice overexpressing calpastatin in pancreatic beta-cells
Calpains are a family of calcium-activated proteases involved in a number of cellular functions including cell death, proliferation and exocytosis. The finding that variation in the calpain-10 gene increases type 2 diabetes risk in some populations has increased interest in determining the potential...
Kaydedildi:
| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044710/ https://ncbi.nlm.nih.gov/pubmed/21099278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.1.3.9780 |
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