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Overexpression of ZAC Impairs Glucose Stimulated Insulin Translation and Secretion in Clonal Pancreatic Beta-Cells

BACKGROUND: ZAC (Zinc finger protein that regulates Apoptosis and Cell-cycle arrest) is a candidate gene for transient neonatal diabetes mellitus (TNDM). This condition involves severe insulin deficiency at birth that reverses over weeks or months but may relapse with diabetes recurring in later lif...

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Bibliografiske detaljer
Udgivet i:Diabetes Metab Res Rev
Main Authors: Du, Xiaoyu, Ounissi-Benkalha, Houria, Loder, Merewyn K, Rutter, Guy A., Polychronakos, Constantin
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101213/
https://ncbi.nlm.nih.gov/pubmed/22865650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dmrr.2325
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