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Age matters: Grading granule secretion in beta cells

Insulin is stored in secretory granules to facilitate rapid release in response to rising glucose levels, but the mechanisms by which these granules are identified and prioritized for secretion remains unclear. Using a fluorescent timer and flow cytometry–assisted organelle sorting, Yau et al. devel...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Georgiadou, Eleni, Rutter, Guy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335800/
https://ncbi.nlm.nih.gov/pubmed/32620690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.014586
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