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Age matters: Grading granule secretion in beta cells

Insulin is stored in secretory granules to facilitate rapid release in response to rising glucose levels, but the mechanisms by which these granules are identified and prioritized for secretion remains unclear. Using a fluorescent timer and flow cytometry–assisted organelle sorting, Yau et al. devel...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Georgiadou, Eleni, Rutter, Guy A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335800/
https://ncbi.nlm.nih.gov/pubmed/32620690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.014586
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