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Yeast one-hybrid screen of a thymus epithelial library identifies ZBTB7A as a regulator of thymic insulin expression

Insulin self-tolerance is, to a large extent, assured by the expression of small quantities of insulin by medullary thymic epithelial cells (mTECs). Regulation of thymic insulin expression differs from that in pancreas and its therapeutic manipulation could play an important role in the prevention o...

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Autores principales: ST-JEAN, Julien R., OUNISSI-BENKALHA, Houria, POLYCHRONAKOS, Constantin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783542/
https://ncbi.nlm.nih.gov/pubmed/23911422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2013.05.238
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