載入...
Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion.
Molecular scanning of human insulin receptor substrate (Irs) genes revealed a single lrs1 prevalent variant, a glycine to arginine change at codon 972 (G972R); previous in vitro studies had demonstrated that the presence of this variant results in an impaired activation of the insulin signalling pat...
Na minha lista:
| 發表在: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley & Sons, Ltd
2008
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506174/ https://ncbi.nlm.nih.gov/pubmed/18208559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00246.x |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|