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Impaired insulin secretion in transgenic mice overexpressing calpastatin in pancreatic beta-cells
Calpains are a family of calcium-activated proteases involved in a number of cellular functions including cell death, proliferation and exocytosis. The finding that variation in the calpain-10 gene increases type 2 diabetes risk in some populations has increased interest in determining the potential...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044710/ https://ncbi.nlm.nih.gov/pubmed/21099278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.1.3.9780 |
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