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ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining
The human disorder ataxia telangiectasia (AT), which is characterized by genetic instability and neurodegeneration, results from mutation of the ataxia telangiectasia mutated (ATM) kinase. The loss of ATM leads to cell cycle checkpoint deficiencies and other DNA damage signaling defects that do not...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040963/ https://ncbi.nlm.nih.gov/pubmed/20647759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.14.12363 |
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