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Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism

The parasite Leishmania often relies on gene rearrangements to survive stressful environments. However, safeguarding a minimum level of genome integrity is important for cell survival. We hypothesized that maintenance of genomic integrity in Leishmania would imply a leading role of the MRE11 and RAD...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Principais autores: Laffitte, Marie-Claude N., Leprohon, Philippe, Hainse, Maripier, Légaré, Danielle, Masson, Jean-Yves, Ouellette, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912120/
https://ncbi.nlm.nih.gov/pubmed/27314941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006117
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