A mechanistic basis for Mre11-directed DNA joining at microhomologies
Repair of DNA double-strand breaks in vertebrate cells occurs mainly by an end-joining process that often generates junctions with sequence homologies of a few nucleotides. Mre11 is critical for this mode of repair in budding yeast and has been implicated in the microhomology-based joining. Here, we...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823903/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.110144297 |
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