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Crystal structure of the Mre11–Rad50–ATPγS complex: understanding the interplay between Mre11 and Rad50

Communication between Mre11 and Rad50 in the MR complex is critical for the sensing, damage signaling, and repair of DNA double-strand breaks. To understand the basis for interregulation between Mre11 and Rad50, we determined the crystal structure of the Mre11–Rad50–ATPγS complex. Mre11 brings the t...

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Autori principali: Lim, Hye Seong, Kim, Jin Seok, Park, Young Bong, Gwon, Gwang Hyeon, Cho, Yunje
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093124/
https://ncbi.nlm.nih.gov/pubmed/21511873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2037811
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