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Formation of Linear Amplicons with Inverted Duplications in Leishmania Requires the MRE11 Nuclease
Extrachromosomal DNA amplification is frequent in the protozoan parasite Leishmania selected for drug resistance. The extrachromosomal amplified DNA is either circular or linear, and is formed at the level of direct or inverted homologous repeated sequences that abound in the Leishmania genome. The...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4256157/ https://ncbi.nlm.nih.gov/pubmed/25474106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004805 |
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