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Formation of Linear Amplicons with Inverted Duplications in Leishmania Requires the MRE11 Nuclease

Extrachromosomal DNA amplification is frequent in the protozoan parasite Leishmania selected for drug resistance. The extrachromosomal amplified DNA is either circular or linear, and is formed at the level of direct or inverted homologous repeated sequences that abound in the Leishmania genome. The...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Laffitte, Marie-Claude N., Genois, Marie-Michelle, Mukherjee, Angana, Légaré, Danielle, Masson, Jean-Yves, Ouellette, Marc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256157/
https://ncbi.nlm.nih.gov/pubmed/25474106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004805
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