Linear amplicons as precursors of amplified circles in methotrexate-resistant Leishmania tarentolae.

Gene amplification is frequently observed in Leishmania cells selected for drug resistance. By gene targeting we have tagged both alleles of the H locus of Leishmania tarentolae with the neomycin and hygromycin phosphotransferase genes ( neo and hyg ). Selection of these recombinant parasites for lo...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Grondin, K, Kündig, C, Roy, G, Ouellette, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9649621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.14.3372
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