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Amplified DNAs in laboratory stocks of Leishmania tarentolae: extrachromosomal circles structurally and functionally similar to the inverted-H-region amplification of methotrexate-resistant Leishmania major.

We describe the structure of amplified DNA that was discovered in two laboratory stocks of the protozoan parasite Leishmania tarentolae. Restriction mapping and molecular cloning revealed that a region of 42 kilobases was amplified 8- to 30-fold in these lines. Southern blot analyses of digested DNA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Petrillo-Peixoto, M L, Beverley, S M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1988
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC365621/
https://ncbi.nlm.nih.gov/pubmed/3244352
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