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Formation of extrachromosomal circular amplicons with direct or inverted duplications in drug-resistant Leishmania tarentolae.

Selection for methotrexate resistance in Leishmania spp. is often associated with amplification of the H locus short-chain dehydrogenase-reductase gene ptr1 as part of extrachromosomal elements. Extensive sequences are always coamplified and often contain inverted duplications, most likely formed by...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Grondin, K, Roy, G, Ouellette, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1996
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC231354/
https://ncbi.nlm.nih.gov/pubmed/8668175
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