Formation of extrachromosomal circular amplicons with direct or inverted duplications in drug-resistant Leishmania tarentolae.
Selection for methotrexate resistance in Leishmania spp. is often associated with amplification of the H locus short-chain dehydrogenase-reductase gene ptr1 as part of extrachromosomal elements. Extensive sequences are always coamplified and often contain inverted duplications, most likely formed by...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
1996
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.7.3587 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|