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Microhomology-mediated end joining: new players join the team

DNA double-strand breaks (DSBs) are the most deleterious type of DNA damage in cells arising from endogenous and exogenous attacks on the genomic DNA. Timely and properly repair of DSBs is important for genomic integrity and survival. MMEJ is an error-prone repair mechanism for DSBs, which relies on...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Wang, Hailong, Xu, Xingzhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237343/
https://ncbi.nlm.nih.gov/pubmed/28101326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-017-0136-8
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