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Integrin α(IIb)β3: A novel effector of Gα(13)
Under physiological conditions, circulating platelets are discoid in shape.1 On these platelets, the fibrinogen receptor (integrin α(IIb)β(3)) is in a low-affinity state, unable to bind soluble fibrinogen (Fg). Activation by agonists such as ADP and thrombin leads to a change in the conformation of...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038087/ https://ncbi.nlm.nih.gov/pubmed/20930548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.1.13559 |
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